Occupational and environmental health explores how our workplaces and surroundings shape our well-being, from the air we breathe to the chemicals we encounter daily. This vital field investigates the hidden risks of modern life, aiming to prevent illness before it starts by understanding the complex links between our environment and our bodies.

At Gist.Science, we track every new preprint in this category from medRxiv to ensure you stay informed on the latest research. We process each study to provide both clear, plain-language explanations and detailed technical summaries, making cutting-edge science accessible without losing essential nuance.

Below are the latest papers in occupational and environmental health, offering fresh insights into how we can build safer, healthier futures for everyone.

📄 occupational and environmental health

Effectiveness of a 12-week multicomponent occupational lifestyle intervention to increase physical activity among Japanese teleworkers: a cluster randomised controlled trial (TELEWORK study)

This cluster randomised controlled trial found that a 12-week multicomponent occupational lifestyle intervention did not significantly increase daily step counts or reduce sedentary time among Japanese teleworkers compared to a waitlist control group.

Kim, J., Nakata, Y., Wada, A., Kanamori, S., Yoshimoto, T., Tsukinoki, R., Umishio, W., Shiomitsu, T., Yoshioka, N., Yos (…)2026-03-26
📄 occupational and environmental health

Metabolomic Responses to External and Internal Environmental Exposures: Evidence of Lipid and Energy Metabolism Disruption in the Estonian Biobank

This study of the Estonian Biobank demonstrates that long-term external air pollution and internal anthropogenic chemical exposures are measurably reflected in the human plasma metabolome, with recurrent disruptions observed in lipid metabolism, membrane composition, and energy-related pathways.

Oosterwegel, M. J., Vermeulen, R. C. H., Estonian Biobank Research Team,, de Hoogh, K., Hiie, L., Esko, T., Vlaanderen (…)2026-03-19
📄 occupational and environmental health

ADDRESSING THE ROLE OF OCCUPATIONAL EXPOSOME ON PARKINSON'S DISEASE AND PARKINSONISM IN A MATCHED CASE-CONTROL STUDY

This matched case-control study in Italy demonstrates that long-term cumulative occupational exposure, particularly to pesticides and metals, significantly increases the risk of Parkinson's disease and Parkinsonism, with genetic factors and family history also playing critical roles.

Lewis, F., Renzetti, S., Goulett, N., Azmoun, S., Sundar, V., Ali, M., Pitta, L., Shoieb, D., Caci, M., Borghesi, S., Co (…)2026-03-18
📄 occupational and environmental health

The wellbeing paradox: High resilience and psychological distress in the transition out of UK policing

This study reveals a "wellbeing paradox" among UK police officers transitioning out of service, where high resilience coexists with elevated psychological distress, highlighting the critical need for targeted organizational support during the vulnerable anticipatory retirement period to ensure successful civilian transitions.

Vaportzis, E., Edwards, W.2026-03-16
📄 occupational and environmental health

Internal and External Protective Factors Associated with the Secondary Traumatic Stress Component of Compassion Fatigue in Feral Cat Caregivers

This study of 172 feral cat caregivers in Portugal reveals that while institutional support and colony registration do not significantly reduce secondary traumatic stress, factors such as caring for large colonies and unemployment increase risk, whereas older age, family support, and serenity serve as protective buffers, highlighting the need for interventions that address both financial burdens and internal coping mechanisms within a One Health framework.

Costa-Santos, C., Vidal, R., Lisboa, S., Vieira-de-Castro, P., Monteiro, A., Duarte, I.2026-03-06
📄 occupational and environmental health

Association between extreme temperature events and dengue risks in Dhaka City, Bangladesh

This study utilizes Distributed Lag Non-linear Models to analyze weekly dengue data in Dhaka City from 2016 to 2024, revealing that while maximum temperatures between 31.5°C and 33.2°C significantly elevate dengue risk, an increase in weekly heatwave days unexpectedly correlates with a protective effect against infection.

Shahriyar, A., Hanifi, S. M. M. A., Rahman, S. M.2026-03-04
📄 occupational and environmental health

The Effect of Occupational Integration on Musculoskeletal Injury in Female Marines in the Fleet: An Epidemiological Cohort Study

This retrospective cohort study of U.S. Marines from 2011 to 2020 reveals that female sex is a significant independent risk factor for musculoskeletal injuries across most body regions, while service in ground combat and aviation occupations generally offers protective effects compared to services roles, with injury risks notably increasing for females in the post-integration period for specific conditions like shoulder injuries.

Fraser, J. J., Zouris, J. M., Hoch, J. M., Sessoms, P. H., MacGregor, A. J., Hoch, M. C.2026-02-23
📄 occupational and environmental health

Occupational and Environmental Challenges and Effects of COVID-19 Testing Implementation Experienced by HIV Viral Load Laboratory Staff within a Public Health Sector Laboratory in South Africa

This study reveals that the dual mandate of maintaining HIV viral load services while implementing COVID-19 testing in South African public laboratories significantly increased occupational challenges and workload, leading to widespread burnout, anxiety, and retention threats among staff, thereby highlighting an urgent need for formal crisis staffing models and institutionalized mental health support.

Sarang, S., Matingo-Mutava, E., Cassim, N.2026-02-22
📄 occupational and environmental health

Decoding the metabolic blockade effect: PFAS inhibition of organic anion transporters impairs VOC clearance and amplifies neurocognitive decline

This study reveals that per- and polyfluoroalkyl substances (PFAS), particularly PFNA, competitively inhibit renal organic anion transporters to block volatile organic compound (VOC) metabolite clearance, thereby amplifying neurocognitive decline and necessitating a shift toward mixture-based toxicological regulations.

Liang, L., Zhang, S. X., Lin, J. J.2026-02-15